产品货号：
Z24852
中文名称：
PTPN5抗体
英文名称：
Anti-PTPN5 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PTPN5 Antibody |
| 指标别名 | Tyrosine-protein phosphatase non-receptor type 5,Neural-specific protein-tyrosine phosphatase,PTPSTEP,Striatum-enriched protein-tyrosine phosphatase,STEP |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | PTPN5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PTPN5 antibody was raised against an 18 amino acid peptide near the amino terminus of human PTPN5.The immunogen is located within amino acids 180 - 230 of PTPN5. |
| 成分 | PTPN5 antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PTPN5 antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The protein tyrosine phosphatase PTPN5,also known as Striatal enriched phosphatase (STEP),is involved in the regulation of synaptic plasticity and neuronal cell survival,including MAPKs,Src family kinases and NMDA receptors (1).It is expressed in dopaminoceptive neurons of the central nervous system and multiple forms of PTPN5 show differential enrichment in adult brain regions (2).NMDA-mediated activation of PTPN5 is an important mechanism for regulation of Erk activity in neurons (3).Furthermore,PTPN5 is involved in the regulation of both NMDAR and AMPAR trafficking (4,5).PTPN5 may play a role in Alzheimer's disease (1). |
| Uniprot ID | Q86TL6 |
| 基因名全称 | Protein tyrosine phosphatase,non-receptor type 5 (striatum-enriched) |
| 蛋白名全称 | Protein tyrosine phosphatase,non-receptor type 5 (striatum-enriched) |
| 推荐稀释比 | PTPN5 antibody can be used for detection of PTPN5 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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